The Cortisol ELISA Assay Kit is designed for the quantitative determination of Cortisol in human serum by an enzyme immunoassay. This Kit is used for research use only. Cortisol is the most abundant circulating steroid along with also the significant glucocorticoid secreted by the adrenal gland. Cortisol is physiologically successful in blood pressure care and anti-inflammatory action.
It's also involved in calcium absorption, gluconeogenesis in addition to the secretion of uric acid and pepsin. It's increased under-stress scenarios, physical exercise, and outside management of ACTH. You can know more about cortisol ELISA via https://www.bosterbio.com/human-cortisol-elisa-kit-ek7002-boster.html.
Levels of cortisol levels generally may be applied as a sign of adrenal function and the differential diagnosis of Addison's and Cushing's diseases in addition to adrenal hyperplasia and carcinoma. Most circulating cortisol is likely to be the cortisol binding globulin or transcortin and albumin. The free cortisol, which is regarded as the active portion of blood, is roughly 1 to 2 percent.
From the absence of considerable quantities of those cortisol binding proteins in saliva, salivary cortisol is regarded as free and reveals a diurnal rhythm with the greatest levels in the daytime and the lowest amounts at nighttime. Cortisol ELISA kits have been developed to identify the glucocorticoid hormone cortisol.
The secretion of cortisol can be controlled by adrenocorticotropic hormone and also a corticotropin-releasing hormone. It's referred to as a 'stress hormone' because its amounts differ if the body undergoes anxiety. Cortisol is involved in gluconeogenesis, lipolysis, bone formation, and immune reactions.
Cortisol ELISA kits are also used to examine stress reactions, metabolic processes, and metabolic disorders. Full cortisol is measured in extracted samples and in both plasma and serum, while free cortisol is measured in urine and saliva only.